The damage caused by glaucoma can't be reversed. But treatment and regular checkups can
help slow or prevent vision loss, especially if the disease is found in its early stages.
Treatment of glaucoma aims to lower intraocular pressure. Treatment options include
prescription eye drops, oral medicines, laser treatment, surgery — or a combination of
approaches.
Glaucoma treatment often starts with prescription eye drops. Some may decrease eye pressure
by improving how fluid drains from the eye. Others decrease the amount of fluid the eye
makes. Depending on how low the eye pressure needs to be, more than one eye drop may be
prescribed.
Eye drop
Prostaglandins.
Increase the outflow of fluid in the eye, helping to reduce eye pressure. Includes
latanoprost (Xalatan), travoprost (Travatan Z), tafluprost (Zioptan), bimatoprost
(Lumigan), and latanoprostene bunod (Vyzulta). Possible side effects include mild
reddening and stinging of the eyes, darkening of the iris, darkening of the pigment
of the eyelashes or eyelid skin, and blurred vision. Usually prescribed for
once-a-day use.
Eye drop
Beta blockers.
Reduce the production of fluid in the eye, helping to lower eye pressure. Examples
include timolol (Betimol, Istalol, Timoptic) and betaxolol (Betoptic S). Possible
side effects include difficulty breathing, slowed heart rate, lower blood pressure,
impotence and fatigue. Can be prescribed for once- or twice-daily use depending on
your condition.
Eye drop
Alpha-adrenergic agonists.
Reduce the production of the fluid that flows throughout the inside of the eye, and
increase the outflow of fluid. Examples include apraclonidine (Iopidine) and
brimonidine (Alphagan P, Qoliana). Possible side effects include irregular heart
rate, high blood pressure, fatigue, red/itchy/swollen eyes, and dry mouth. Usually
prescribed twice daily; sometimes three times a day.
Eye drop
Carbonic anhydrase inhibitors.
Reduce the production of fluid in the eye. Examples include dorzolamide and
brinzolamide (Azopt). Possible side effects include a metallic taste, frequent
urination, and tingling in the fingers and toes. Usually prescribed twice daily;
sometimes three times a day.
Eye drop
Rho kinase inhibitor.
Lowers eye pressure by suppressing the rho kinase enzymes responsible for fluid
increase. Available as netarsudil (Rhopressa), prescribed once-a-day. Possible side
effects include eye redness and eye discomfort.
Eye drop
Miotic or cholinergic agents.
Increase the outflow of fluid from the eye. An example is pilocarpine (Isopto
Carpine). Side effects include headache, eye pain, smaller pupils, possible blurred
or dim vision, and nearsightedness. Usually prescribed up to four times a day.
Because of potential side effects and frequent daily use, these medicines are not
prescribed very often anymore.
Tip
Because some of the eye drop medicine is absorbed into the bloodstream, you may
experience some side effects unrelated to your eyes. To minimize this absorption, close
your eyes for 1 to 2 minutes after putting the drops in. You also may press lightly at
the corner of your eyes near your nose to close the tear duct for 1 to 2 minutes. Wipe
off any unused drops from your eyelid.
You may be prescribed multiple eye drops or need to use artificial tears. Make sure you
wait at least five minutes in between using different drops.
Eye drops alone may not bring eye pressure down to the desired level. So an eye doctor also
may prescribe oral medicine. This medicine is usually a carbonic anhydrase inhibitor.
Possible side effects include frequent urination, tingling in the fingers and toes,
depression, stomach upset, and kidney stones.