Selective Laser Trabeculoplasty, or SLT, is used when eye drop medications are not
lowering the eye pressure enough or are causing significant side effects. It can also be
used as initial treatment in glaucoma. SLT has been in use for more than 25 years in the
United States and around the world.
- Who is a candidate for SLT?
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Patients who have primary or secondary open-angle glaucoma (the drainage system
in the front part of the eye is open) and are in need of lowering of their
intraocular pressure (IOP) are eligible for the procedure. Your eye doctor will
make the final determination if you are a candidate.
- How does it work?
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Laser energy is applied to the drainage tissue in the eye. This starts a
chemical and biological change in the tissue that results in better drainage of
fluid through the drain and out of the eye. This eventually results in lowering
of IOP. It may take 1–3 months for the results to appear.
- Why is it called Selective?
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The type of laser used has minimal heat energy absorption because it is only
taken up by selected pigmented tissue in the eye. Sometimes it is referred to as
a cold laser. Because of this, the procedure produces less scar tissue and has
minimal pain.
- What are the risks?
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One key aspect of SLT is a favorable side effect profile, even when compared
with glaucoma medications. Post-operative inflammation is common but generally
mild, and treated with observation or eye drops or an oral non-steroidal
anti-inflammatory drug. There is an approximately 5% incidence of IOP elevation
after laser, which can be managed by glaucoma medications and usually goes away
after 24 hours.
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How effective is it and how long does it last?
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SLT lowers the IOP by about 30% when used as initial therapy. This is comparable
to the IOP lowering of the most powerful and commonly used class of glaucoma
medication (prostaglandin analogs). This effect may be reduced if the patient is
already on glaucoma medications. The effect will generally last between 1–5
years, and in some cases, longer than that. If it does not last at least 6–12
months, it is usually not considered successful.
- What happens if it wears off?
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If SLT is effective at lowering IOP but this wears off over several years, the
procedure can be repeated. Repeat treatments may or may not lower IOP as much as
the first, and continued repeat laser will eventually not be effective. If SLT
is not initially successful, repeat treatment is not likely to be effective.
Alternatively, glaucoma medication can be used if the effect wears off over
time.
- What happens if it doesn’t work?
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If SLT fails to lower the IOP, then the glaucoma is treated by other means such
as medications or surgery. The laser does not affect the success of these other
types of treatment.
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Will I still need to use glaucoma medications?
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Some patients can be controlled with just laser treatment. Others require
additional IOP lowering and may therefore need to use glaucoma medication as
well. Think of the SLT as equivalent to one glaucoma medication. It is important
to remember that SLT is not a cure for glaucoma, just as medication and surgery
are not. Whatever method is used to treat glaucoma, appropriate follow up and
testing with your eye care professional is critical.